What GLP-1 Users Are Discovering About Their Skin and Why IVF Science May Hold the Answer.

Skincare Hasn’t Kept Up With the Science That is Changing Our Bodies

While breakthroughs like GLP-1 medications are redefining what’s possible for metabolic health, the science of skincare has remained surprisingly stagnant.

For decades, the industry has largely followed the same patterns:

• Celebrity-driven brands overshadowing real scientific innovation
• Outdated formulations recycled with minor tweaks
• A focus on trendy ingredients rather than biological function
• Marketing-first development instead of science-first thinking
• Temporary surface-level results instead of long-term skin health

At a time when medicine is advancing rapidly—transforming how we approach weight, aging and longevity—skincare has often remained stuck in the past.

But a new approach is beginning to emerge.

A New Approach: Skincare Based on Your Biology, Not Ingredients

Instead of asking which ingredient is trending, a new generation of scientists is asking a different question:

What does skin actually need at the cellular level to function optimally?

This shift is being led by pioneers whose work did not begin in beauty—but in some of the most demanding fields of human biology.

IVF. Regenerative medicine. Cellular science.

In these environments, precision is not optional. Safety is not negotiable. And the health of delicate cells depends entirely on the quality of their environment.

That same philosophy is now being applied to skincare.



GLP-1: What Skincare Can—and Cannot—Do

GLP-1 medications are part of a broader transformation in how people approach health, longevity and aging.

But while these medications can change the body, they also highlight an important truth:

Not all changes can be addressed in the same way.

Skincare cannot restore lost facial fat or fully reverse structural changes caused by weight loss.

But it can play a meaningful role in supporting the skin itself.

During a GLP-1 journey, skin may benefit from:

• Improved hydration
• Enhanced barrier support
• Better texture and smoothness
• Increased resilience
• A more luminous, healthy-looking appearance

This is where skincare becomes part of a larger, more holistic approach to wellness.

Why the Face Changes During Weight Loss

The face contains layers of fat that help support its contours and give skin a fuller, smoother appearance.

When weight is lost—especially quickly—some of that volume is reduced. Skin may not adapt at the same pace, particularly as collagen and elastin naturally decline with age.

This can lead to:

• A more hollow appearance
• Increased laxity
• More visible lines and folds

At the same time, reduced appetite can impact nutrient intake—making it even more important to ensure the body is properly supported.

Skin is visible, but it is not the body’s top priority.

Which is why supporting it intentionally matters.

From IVF Labs to Skin Science

Before AV Laboratories developed skincare, its scientists were working in IVF and regenerative medicine—fields where cellular nourishment, balance and purity are critical.

The cells involved in reproductive science are among the most sensitive in the human body. Their survival depends on carefully controlled environments and precisely delivered nutrients.

This work led to a powerful insight:

If nourishing delicate cells can support their health in the lab, could the same biology-first approach support skin?

Instead of building products around a single ingredient, AV Laboratories built its approach around three core pillars:

• Innovation — Translating decades of cellular science into skincare
• Efficacy — Designing formulas that deliver visible, measurable results
• Safety — Applying the same precision standards used in medical science

This is not skincare inspired by trends.

It is skincare shaped by biology.

Benefits for users and those on GLP-1's

The result is a new category of skincare focused on molecular nourishment—supporting skin with the building blocks it needs to appear healthier, stronger and more resilient over time.

Rather than temporarily masking concerns, this approach works to improve:

• Hydration at a deeper level
• Skin texture and smoothness
• The appearance of firmness and elasticity
• Overall radiance and vitality

Early users often report visible improvements in how their skin looks and feels—appearing more luminous, more resilient and more balanced.

Why So Many People Feel Frustrated With Skincare

For years, consumers have largely been offered two extremes.

At one end are trend-driven products that promise transformation but deliver little more than temporary hydration.

At the other are expensive procedures, recurring appointments and injectable treatments that can require needles, downtime and continued maintenance.

Many people want another option: skincare approachable enough to use every day, but advanced enough to deliver visible results.

> Skincare That Does Not Deliver
Many products create a temporary cosmetic effect without producing meaningful visible improvement over time.

> Expensive In-Person Treatments
Procedures and recurring appointments can quickly become costly, time-consuming and difficult to maintain.

> Needles and Aggressive Procedures
Not everyone wants injectables, discomfort or downtime to be part of their regular beauty routine.

>Trend-Driven Ingredients Without Real Science
An ingredient may sound impressive, but its concentration, stability, supporting formula and finished-product testing matter far more than the name on the bottle.

AV Laboratories believed there had to be a more intelligent way forward.

Founded by Pioneers in IVF Solutions

Now Reimagining the Science of Skin Aging

AV Laboratories was founded by Ami and Monica Mezezi, pioneers with more than 25 years of experience in regenerative medicine, stem-cell science and IVF solutions.

Their earlier work focused on one of the most delicate challenges in bioscience: creating the precise molecular environment that early cells require to survive, develop and thrive.

They helped build an IVF solutions business that was ultimately sold in a transaction valued at $125 million.

But the greater value was the knowledge accumulated along the way.

Their work revealed the importance of giving cells the correct molecular building blocks, in the correct balance, at the correct time.

That insight inspired a new question:

What if the same approach used in IVF solutions, could be applied to the appearance of skin aging?

Together with a world-class team of scientists, doctors and formulators, they spent years developing a biotechnology designed around the molecular needs of healthy-looking skin.

The result was AVL SOM3®.

For the first time, 25 years of bioscience innovation were being applied to a daily skincare formula designed to support visible skin wellness and longevity.

See What Can Change in 28 Days

AVL Face Serum is a lightweight, high-efficacy formula designed to deliver progressive visible improvement without adding unnecessary steps to your routine.

Apply it morning and evening to clean skin, followed by your preferred moisturizer.

AVL products have been clinically evaluated across more than 1,300 participants, with testing focused on visible improvements in skin appearance and wellness.

Clinical testing has shown improvements in:

• Fine lines and wrinkles
• Skin firmness
• Elasticity
• Hydration and moisture
• Skin texture
• Uneven-looking tone
• Radiance

The goal is simple: visible change you can see and feel without turning skincare into a complicated ten-step ritual.

One serum. Morning and night. Twenty-eight days.

What Happens to Skin as We Age?

In younger skin, renewal happens more quickly and the systems responsible for structure, elasticity and cellular energy operate more efficiently.

Over time, those processes begin to slow.

Collagen and elastin levels decline. Cellular energy pathways become less efficient. Skin may take longer to recover from daily stress.

The visible effects may include:

• Fine lines and wrinkles
• Uneven texture
• Dullness and dark spots
• Crepey-looking skin
• Loss of firmness
• Increased sensitivity and visible redness

To understand AVL SOM3®, it helps to understand the three foundations of younger-looking skin.

The Three Foundations of Younger-Looking Skin

Structure

Collagen helps give skin its firm, supported appearance. As collagen declines, lines become more visible and skin may appear thinner or less firm.

Elasticity

Elastin contributes to the visible flexibility and resilience that allow skin to appear smooth and supple.

Energy

NAD+ plays an important role in cellular energy and processes associated with renewal, recovery and healthy-looking radiance.

Together, structure, elasticity and energy influence how firm, smooth, luminous and resilient skin appears over time.

But there is a problem.

Collagen, Elastin and NAD+ Cannot Simply Be Delivered Through the Surface

Collagen creams. Elastin serums. NAD+ skincare.

The message is always similar: apply more of what aging skin is losing.

What is often left unsaid is that these molecules cannot simply be applied topically and delivered intact to the deeper areas where skin uses them.

AV Laboratories took a different approach.

Do not give skin what it cannot use. Give it the building blocks it understands.

The AVL SOM3® Breakthrough

Amino acids are fundamental molecular building blocks used throughout the body in processes associated with proteins such as collagen and elastin.

AVL SOM3® contains all 20 amino acids in a patented, precisely balanced system developed to support the visible foundations of skin wellness:

• Structure
• Elasticity
• Energy

Rather than attempting to place finished collagen, elastin or NAD+ into the skin, AVL SOM3® delivers molecular nourishment designed to support the skin’s natural processes associated with a firmer, smoother and more radiant appearance.

Developed through:

• More than five years of dedicated development
• More than $10 million in research and development
• A team of leading biotechnology scientists
• A patented complex containing all 20 amino acids
• Manufacturing in an FDA-registered facility
• Clinical testing under dermatological supervision

This is not another single-ingredient trend.

It is a complete molecular system designed around what healthy-looking skin needs to appear firmer, smoother, more radiant and more resilient over time.

One Peptide Is Not Enough

But healthy-looking skin depends on more than one pathway and more than one ingredient.

AVL SOM3® delivers all 20 amino acids in a precise, patented system designed to support the visible foundations of skin structure, elasticity and energy.

Together, they create a more complete approach:

• Peptide technology for smoother-looking expression lines
• All 20 amino acids for precision molecular nourishment
• Support for firmer, more elastic-looking skin
• Hydration for softness, comfort and glow
• Barrier support for greater visible resilience
• A lightweight formula designed for consistent daily use

Lasting visible improvement does not come from chasing one miracle ingredient.

It comes from a thoughtfully engineered formula in which every component has a purpose.

Your 28-Day Protocol

AVL Face Serum

Apply a small amount to clean skin every morning and evening.

Gently smooth the serum across the face and neck, allowing it to absorb before applying moisturizer or sunscreen.

The lightweight formula is designed to support:

• Smoother-looking fine lines and wrinkles
• Firmer, more elastic-looking skin
• More even-looking tone
• Refined skin texture
• Increased moisture and radiance
• A healthier, more rested appearance

It takes only a few seconds, twice a day.

Consistency does the rest.

What to Expect

Day 1: Nourish and Hydrate

Skin begins receiving lightweight moisture and precision molecular nourishment. It may immediately feel softer, smoother and more comfortable.

Day 7: A Fresher-Looking Surface

With consistent use, skin may begin to feel smoother and appear more refreshed, hydrated and radiant.

Day 14: Visible Improvement Builds

Texture, hydration and the appearance of fine lines may begin to show more noticeable improvement.

Day 28: Your Transformation Is Revealed

After 28 days of consistent use, skin may appear smoother, firmer, more hydrated, more even and more youthful-looking.

But 28 days is not the finish line.

It is the beginning of a more intelligent approach to how your skin appears to age.

The real value of molecular serum.

A single injectable treatment can cost several hundred dollars and require recurring appointments.

A shelf filled with disconnected products can cost just as much, without being formulated or clinically tested as one complete system.

AVL Face Serum brings together:

• Patented AVL SOM3® biotechnology
• Acetyl Hexapeptide-8
• All 20 amino acids
• More than five years of development
• More than $10 million in research and development
• Clinical testing
• Precision formulation
• Lightweight daily hydration
• A 28-day protocol designed for visible results
• A long-term approach to skin wellness and longevity

This is not the price of one fashionable peptide.

It represents decades of bioscience, years of development and a patented technology designed to expand what daily skincare can do.

Healthy-Looking Skin Belongs to All of Us

Healthy-looking skin belongs to all of us, at every age and every stage of life.

AV Laboratories is building a community around a new vision for skincare: using the power of bioscience to support lasting skin wellness, resilience and radiance.

The goal is not to freeze time.

It is to help your skin look its best through every chapter ahead.

Your best skin is still be ahead.