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Most skincare starts with ingredients.

We start with your biology.

Most skincare starts with ingredients.

We start with your biology.

25 years of work in regenerative medicine taught us what the body’s most delicate cells need to thrive, supporting over one million new lives. Today, those same discoveries are unlocking a new approach to younger-looking skin, one that nourishes cells instead of simply treating symptoms.
The future of skincare is longevity. Join in.

  • Clinically Tested1300+ People
  • Recommended byTop Dermatologists
  • Visible Results InOnly 28 Days
  • Clinical GradeIngredients
  • Medical GradeSafety & Purity
AVL IN THE MEDIA
Clinically Tested on 1300+ Patients

Visible results in 28 days.

Every AVL formula undergoes rigorous internal and independent third-party testing, from molecular validation to dermatological and clinical testing, ensuring exceptional safety and visible performance. Clinical results documented using VISIA® facial imaging technology.

"A breakthrough in skin longevity." Dr. Olena Ivchenko, MD

AVL SOM3® The most advanced skin longevity platform. Engineered to nourish skin at the molecular level for healthy-looking skin at any age.

6 Signs of Under-Nourished Skin

As skin ages, it loses essential nutrients. As those levels decline, visible signs of aging appear more quickly.

01
Appearance of Fine Lines & WrinklesSkin lacks Collagen for structure and support.
02
Uneven Skin TextureSkin lacks Elastin for "bounce" and NAD+ for renewal.
03
Appearance of Dark SpotsSkin lacks NAD+ for renewal.
04
"Crepey" SkinCollagen declines, skin has less support.
05
Loss of FirmnessLess collagen and elastin, less structure and bounce.
06
Appearance of Redness & IrritationLow NAD+ levels leads to slowing renewal.
AVL SOM3® is the first skincare technology designed to activate all three biological pillars of skin longevity: Structure, Elasticity, and Energy. Its patented blend of amino acids provides the molecular building blocks skin needs to support collagen, elastin, and cellular energy for a firmer, more youthful appearance.
Feed your skin what it is missing — AVL SOM3
LOOK CLOSER

Built on
5 Years of Development

Backed by
$10 Million in R&D

Created by
Leading Biotech Scientists

Contains
All 20 Amino Acids

Manufactured in our
FDA Approved Facility

Purity is Performance.

Our work in IVF and regenerative medicine taught us that even small impurities can disrupt the environment cells need to thrive. Purity is essential to long-term wellness and the engine behind our formulations. By removing what does not belong and delivering only what skin needs, we help every molecule perform at its highest level. That commitment extends through continuous laboratory research, in-house formulation, rigorous testing, and clinical trials, with every product held to exacting standards for purity, precision, safety, and performance.

AVL SOM3® Manufactured in our FDA Approved Facility
Clinically Tested Under Dermatological Control
Laboratory Researched & Validated on Molecular Level
Third Party, Double Blind Trials
The people behind AVL

A new vision for lifelong skin wellness.

Founders

For decades, co-founders Ami and Monica Mezezi pioneered solutions in IVF, regenerative medicine, and stem-cell science, working with some of the body’s most delicate cells. They learned that cells thrive when given the right environment, precise nourishment, and consistent support.

That question became AVL. Together with a world-class team of scientists and doctors, Ami and Monica are developing breakthrough technologies that redefine how we approach the appearance of skin aging and support lasting skin wellness.

"Healthy-looking skin belongs to all of us, at every age and every stage of life. We founded AVL around a new vision for skincare: not simply reacting to the signs of aging, but helping everyone support lasting skin wellness, resilience, and radiance."
- Ami

The People Behind AVL

Learn More About Us
Dr. Dendy Engelman, MD, FAAD
AVL Scientific Advisory Board

Dr. Dendy Engelman, MD, FAAD

Dermatologist

Dr. Dendy Engelman is a board certified dermatologist, Mohs surgeon, and leader in medical, cosmetic, and surgical dermatology. She is focused on helping AVL advance the next generation of longevity focused skincare.

Sylwia Pawlaczyk Ms
AVL Master Formulator, COO

Sylwia Pawlaczyk Ms

Master Formulator

Sylwia is a chemist with deep expertise in advanced skincare science, bringing together cutting-edge formulations, scientific validation, and an uncompromising commitment to transparency and sustainability. She helps create products that are as elegant as they are effective, developed with the highest standards for skin, safety, efficacy, and the environment.

Dr. Olena Ivchenko, MD
AVL SCIENTIFIC ADVISORY BOARD

Dr. Olena Ivchenko, MD

Aesthetic Medicine

Dr. Ivchenko is a skin health expert with a focus on aesthetic medicine, specializing in advanced skin treatment protocols and combined therapies. She supports AVL clinical studies investigating skin processes and the use of AVL for post-treatment wellness.

Vanesa Kodra, PA-C
AVL SCIENTIFIC ADVISORY BOARD

Vanesa Kodra, PA-C

Cosmetic Dermatology

Vanesa is an expert in medical and cosmetic dermatology, specializing in the use of advanced science-backed formulations for the treatment of skin concerns and overall wellness. She supports AVL’s patient advocacy for in-treatment, post-treatment, and daily use, ensuring the highest levels of personal care.

Dr. Kevin Flynn, PHD
AVL Scientific Advisory Board

Dr. Kevin Flynn, PHD

Molecular Biologist

Dr. Flynn is a stem cell and gene therapy research scientist passionate about advancing next-generation innovation for consumers in cell therapy, organoids, and neuroscience. He is currently investigating AVL SOM3® on the molecular level and it's effect on skin wellness.

Join those experiencing transformative results.

This is an at-home treatment you must try!

Skin immediately begins to feel more hydrated, balanced, and nourished. These effects increase over time.

-Ethan Ung

Visible results in just a few weeks.

My skin tone looks more even and my fine lines are noticeably softer. The texture is incredible.

-Mia Carter

The glow is real.

I get compliments on my skin all the time now. It feels healthier and more resilient than ever.

-Nora Bennett

Worth every penny.

Premium feel, premium results. My morning routine is shorter and my skin has never looked better.

-Olivia Reyes

Dr. Olena Ivchenko, M.D.

Scientists love AVL

"AVL transformed my skin. It helped to remove my fine lines and wrinkles. It's my go-to recommendation for patients who want younger looking, more radiant skin, with proven formulas that are safe."
Dr. Olena Ivchenko, M.D.Aesthetic Medicine
THE LUXURY OF PRECISION

Every molecule matters.

Extraordinary skincare demands extraordinary precision. When working at the molecular level, even the smallest details matter. That’s why we oversee research, formulation, manufacturing, and testing across three specialized facilities on two continents, maintaining control over every stage to protect purity, safety, and consistency. The result is skincare you can trust and feel good about using every day, for yourself and the people you love.

A New Age In Skincare Formulation

Formulated to evolve
with your skin.

Our advanced formulation weaves a precise tapestry of clinical-grade actives designed to adapt to your skin's ever-changing needs.

By accounting for environmental stressors, hormonal shifts, and lifestyle factors, it delivers a comprehensive, 360-degree approach to addressing fine lines and wrinkles—supporting smoother, more resilient skin at every level.

Learn More About Our Formulations
AVL Formulation

Our advanced formulation weaves a precise tapestry of clinical-grade actives designed to adapt to your skin's ever-changing needs.

By accounting for environmental stressors, hormonal shifts, and lifestyle factors, it delivers a comprehensive, 360-degree approach to addressing fine lines and wrinkles—supporting smoother, more resilient skin at every level.

Learn More About Our Formulations
Shop With Confidence

Shop With Confidence

Experience AVL risk free.

Covered by our money-back guarantee.