Face Cream Rich

A subjective evaluation questionnaire, prepared by the clinical trial center was filled in by the subjects at the end of the study - after 28 days of using product.

Skin texture of trial participant on day 0 and after 28 days of using product twice a day, captured by VISIA® Skin Analysis System.

SUBJECTIVE EVALUATION QUESTIONNAIRE

A subjective evaluation questionnaire, prepared by the clinical trial center was filled in by the subjects at the end of the study - after 28 days of using product.

Smooth Skin

100%

believe skin is smoothed

Hydrated Skin

100%

believe the skin feels instantly and deeply hydrated

Moisturized Skin

96%

believe their skin is moisturized

Regenerated Skin

96%

believe their skin is regenerated

Skin Complexion

96%

believe their skin feels plump and firmer

93%

believe the appearance of fine lines and wrinkles is reduced

CLINICAL EVALUATION OF Smoothing, anti-wrinkle, Moisturizing, firmness effect

The product smoothing/anti-wrinkle by measurements using 3D Primos-CR® System, effect on the skin biomechanical properties by measurements using Cutometer® and moisturizing effect by measurements using Corneometer® on day 0 and after 28 days of using the product. The trial was conducted under
dermatological control.

Smoothing Effect

Day 0
-1.3
Day 28
0.6

-7%

a significant decrease in average roughness

Smoother skin was observed in 50% of subjects

Anti-Wrinkle (average relief)

Day 0
-4.3
Day 28
2.5

-4%

a limit significant decrease in average relief parameter

A tendency to less wrinkled skin
was observed in 54% of subjects

Anti-Wrinkle (maximum relief)

Day 0
-10
Day 28
5.7

-6%

a limit significant maximum relief

A tendency to less wrinkled skin
was observed in 58% of subjects

Less Wrinkled Skin (average wrinkle depth)

Day 0
-4.5
Day 28
4.1

-5%

a limit significant decrease in average wrinkles

A tendency to less wrinkled skin by volume reduction was observed in 71% of subjects

Firmness

Day 0
-0.083
Day 28
0.013

19%

a significant improvement in cutaneous firmness

Firmer skin was observed
in 93% of subjects

Cutaneous Barrier Reinforcement (Elasticity)

Day 0
 0.105
Day 28
0.035

22%

a significant improvement in net elasticity

More elastic skin was
observed in 82% of subjects

EVALUATION OF THE OCULAR POTENTIAL IRRITANCY

The cytotoxicity is evaluated by measuring the mean diameter (MD) of cell lysis in agarose gel on 4 dishes and calculating the mean. This value is presented in centimeters, to one decimal place.

AVL reference product

MD [cm]

Classification

Conclusion

Face Cream - Rich

0.0

Low cytotoxicity

The test item does not have irritant properties

EVALUATION OF THE SKIN COMPATIBILITY

Measured after single application on adult subjects under dermatological control.

100 subjects – 50 sensitive skin and 50 normal skin, where M.C.I.I. = Mean Cumulative Irritation Index

AVL reference product

Skin Type

Concentration / Type

Patch duration

M.C.I. I.

Conclusion

Face Cream - Rich

Normal

20 μl Pure / Occlusive

48 hours

0.00

Non irritating

Face Cream - Rich

Sensitive

20 μl Pure / Occlusive

48 hours

0.03

Non irritating