Face Serum

A subjective evaluation questionnaire, prepared by the clinical trial center was filled in by the subjects at the end of the study - after 28 days of using product.

The skin of trial participant showing wrinkles on day 0 and after 28 days of using product twice a day, captured by VISIA® Skin Analysis System.

SUBJECTIVE EVALUATION QUESTIONNAIRE

A subjective evaluation questionnaire, prepared by the clinical trial center was filled in by the subjects at the end of the study - after 28 days of using product.

ANTI-WRINKLE

92%

believe that wrinkles are reduced

92%

believe wrinkles are filled

96%

believe this serum reduces the appearance of fine lines & wrinkles

Tighter Skin

93%

believe their skin looks lifted and tighter

Firmness

100%

believe their skin feels plump and firmer

100%

believe their skin is regenerated and smooth

96%

believe their skin looks and feels balanced

CLINICAL EVALUATION OF SMOOTHING, ANTI-WRINKLE, MOISTURIZING, FIRMNESS EFFECT

The product smoothing/anti-wrinkle by measurements using 3D Primos-CR® System, effect on the skin biomechanical properties by measurements using Cutometer® and moisturizing effect by measurements using Corneometer® on day 0 and after 28 days of using the product. The trial was conducted under
dermatological control.

FIRMNESS

Day 0
0.474
Day 28
0.368

+22%

a significant improvement in cutaneous firmness

Firmer skin was observed in 100% of subjects.

BIOLOGICAL ELASTICITY

Day 0
0.522
Day 28
0.697

+33%

improvement in cutaneous biological elasticity

More elastic skin was observed in 73% of subjects

RAW ELASTICITY

Day 0
0.288
Day 28
0.368

+28%

improvement in raw elasticity

More elastic skin was observed in 77% of subjects

Moisturizing (cutaneous hydration rate)

Day 0
49.7
Day 28
57.1

15%

improvement in hydration level

96% of subjects presenting an improvement

Anti-Wrinkle (average relief)

Day 0
71.4
Day 28
68.3

+65%

anti-wrinkle effect

A tendency to less wrinkled skin was observed in 65% of subjects

ANTI-WRINKLE (maximum relief)

Day 0
122.9
Day 28
116.3

+70%

anti-wrinkle effect

A tendency to less wrinkled skin was observed in 70% of subjects

EVALUATION OF THE OCULAR POTENTIAL IRRITANCY

The cytotoxicity is evaluated by measuring the mean diameter (MD) of cell lysis in agarose gel on 4 dishes and calculating the mean. This value is presented in centimeters, to one decimal place.

AVL reference product

MD [cm]

Classification

Conclusion

Face Serum

0.0

Low cytotoxicity

The test item does not have irritant properties

EVALUATION OF THE SKIN COMPATIBILITY

Measured after single application on adult subjects under dermatological control.

100 subjects – 50 sensitive skin and 50 normal skin, where M.C.I.I. = Mean Cumulative Irritation Index

AVL reference product

Skin Type

Concentration / Type

Patch duration

M.C.I. I.

Conclusion

Face Serum

Normal

20 μl Pure / Occlusive

48 hours

0.12

Non irritating

Face Serum

Sensitive

20 μl Pure / Occlusive

48 hours

0.06

Non irritating